Volume 13 Issue 1
Feb.  2022
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Andrea L. Moreno-Ríos, Lesly P. Tejeda-Benítez, Ciro F. Bustillo-Lecompte. Sources, characteristics, toxicity, and control of ultrafine particles: An overview[J]. Geoscience Frontiers, 2022, 13(1): 101147. doi: 10.1016/j.gsf.2021.101147
Citation: Andrea L. Moreno-Ríos, Lesly P. Tejeda-Benítez, Ciro F. Bustillo-Lecompte. Sources, characteristics, toxicity, and control of ultrafine particles: An overview[J]. Geoscience Frontiers, 2022, 13(1): 101147. doi: 10.1016/j.gsf.2021.101147

Sources, characteristics, toxicity, and control of ultrafine particles: An overview

doi: 10.1016/j.gsf.2021.101147

This work was carried out by partial financial support from Colciencias, Colombia (Project 141180764164, Contract 815-2018). Special thanks to Prof. Camilo A. Castro for his suggestions towards the literature review approach.

  • Received Date: 2020-10-08
  • Accepted Date: 2021-01-14
  • Rev Recd Date: 2021-01-04
  • Publish Date: 2021-01-20
  • Air pollution by particulate matter (PM) is one of the main threats to human health, particularly in large cities where pollution levels are continually exceeded. According to their source of emission, geography, and local meteorology, the pollutant particles vary in size and composition. These particles are conditioned to the aerodynamic diameter and thus classified as coarse (2.5–10 μm), fine (0.1–2.5 μm), and ultrafine (<0.1 μm), where the degree of toxicity becomes greater for smaller particles. These particles can get into the lungs and translocate into vital organs due to their size, causing significant human health consequences. Besides, PM pollutants have been linked to respiratory conditions, genotoxic, mutagenic, and carcinogenic activity in human beings. This paper presents an overview of emission sources, physicochemical characteristics, collection and measurement methodologies, toxicity, and existing control mechanisms for ultrafine particles (UFPs) in the last fifteen years.
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    Abbas, I., Badran, G., Verdin, A., Ledoux, F., Roumié, M., Courcot, D., Garçon, G., 2018. Polycyclic aromatic hydrocarbon derivatives in airborne particulate matter: sources, analysis and toxicity. Environ. Chem. Lett. 16, 439-475. https://doi.org/10.1007/s10311-017-0697-0
    Abdel-Shafy, H.I., Mansour, M.S.M., 2016. A review on polycyclic aromatic hydrocarbons: Source, environmental impact, effect on human health and remediation. Egypt. J. Pet. 25(1), 107-123. https://doi.org/10.1016/j.ejpe.2015.03.011
    Abramesko, V., Tartakovsky, L., 2017. Ultrafine particle air pollution inside diesel-propelled passenger trains. Environ. Pollut. 226, 288-296. https://doi.org/10.1016/j.envpol.2017.03.072
    Agudelo-Castañeda, D.M., Teixeira, E.C., Schneider, I., Lara, S.R., Silva, L.F.O., 2017. Exposure to polycyclic aromatic hydrocarbons in atmospheric PM1.0 of urban environments: Carcinogenic and mutagenic respiratory health risk by age groups. Environ. Pollut. 224, 158-170. https://doi.org/10.1016/j.envpol.2017.01.075
    Agudelo-Castañeda, D.M., Teixeira, E.C., Braga, M., Rolim, S.B.A., Silva, L.F.O., Beddows, D.C.S., Harrison, R.M., Querol, X., 2019. Cluster analysis of urban ultrafine particles size distributions. Atmos. Pollut. Res. 10(1), 45-52. https://doi.org/10.1016/j.apr.2018.06.006
    Allen, J.L., Oberdörster, G., Morris-Schaffer, K., Wong, C., Klocke, C., Sobolewski, M., Conrad, K., Mayer-Proschel, M., Cory-Slechta, D.A., 2017. Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology 59, 140-154. https://doi.org/10.1016/j.neuro.2015.12.014
    Azarmi, F., Kumar, P., 2016. Ambient exposure to coarse and fine particle emissions from building demolition. Atmos. Environ. 137, 62-79. https://doi.org/10.1016/j.atmosenv.2016.04.029
    Azarmi, F., Kumar, P., Mulheron, M., 2014. The exposure to coarse, fine and ultrafine particle emissions from concrete mixing, drilling and cutting activities. J. Hazard. Mater. 279, 268-279. https://doi.org/10.1016/j.jhazmat.2014.07.003
    Azarmi, F., Kumar, P., Marsh, D., Fuller, G., 2016. Assessment of the long-term impacts of PM10 and PM2.5 particles from construction works on surrounding areas. Environ. Sci.: Process. Impacts 18(2), 208-221. https://doi.org/10.1039/c5em00549c
    Badran, G., Ledoux, F., Verdin, A., Abbas, I., Roumie, M., Genevray, P., Landkocz, Y., Guidice, J.M.L., Garçon, G., Courcot, D., 2020. Toxicity of fine and quasi-ultrafine particles: Focus on the effects of organic extractable and non-extractable matter fractions. Chemosphere 243, 125440. https://doi.org/10.1016/j.chemosphere.2019.125440
    Bhargava, A., Tamrakar, S., Aglawe, A., Lad, H., Kumar, R.S., Kumar, D., Tiwari, R., Chaudhury, K., Yu, I., Kumar, P., 2018. Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage. Environ. Pollut. 234, 406-419. https://doi.org/10.1016/j.envpol.2017.11.093
    Bhargava, A., Shukla, A., Bunkar, N., Shandilya, R., Lodhi, L., Kumari, R., Gupta, P.K., Rahman, A., Chaudhury, K., Tiwari, R., Goryacheva, I.Y., Mishra, P.K., 2019. Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications. Environ. Pollut. 252, 39-50. https://doi.org/10.1016/j.envpol.2019.05.065
    Billet, S., Landkocz, Y., Martin, P.J., Verdin, A., Ledoux, F., Lepers, C., André, V., Cazier, F., Sichel, F., Shirali, P., Gosset, P., Courcot, D., 2018. Chemical characterization of fine and ultrafine PM, direct and indirect genotoxicity of PM and their organic extracts on pulmonary cells. J. Environ. Sci. 71, 168-178. https://doi.org/10.1016/j.jes.2018.04.022
    Bliss, B., Tran, K.I., Sioutas, C., Campbell, A., 2018. Ambient ultrafine particles activate human monocytes: Effect of dose, differentiation state and age of donors. Environ. Res. 161, 314-320. https://doi.org/10.1016/j.envres.2017.11.019
    Bourdrel, T., Bind, M.A., Béjot, Y., Morel, O., Argacha, J.F., 2017. Cardiovascular effects of air pollution. Arch. Cardiovasc. Dis. 110(11), 634-642. https://doi.org/10.1016/j.acvd.2017.05.003
    Briffa, J., Sinagra, E., Blundell, R., 2020. Heavy metal pollution in the environment and their toxicological effects on humans. Heliyon 6(9), e04691. https://doi.org/10.1016/j.heliyon.2020.e04691
    Buiarelli, F., Di Filippo, P., Massimi, L., Pomata, D., Riccardi, C., Simonetti, G., Sonego, E., 2019. Ultrafine, fine and coarse airborne particle mass concentration in workplaces. Atmos. Pollut. Res. 10(5), 1685-1690. https://doi.org/10.1016/j.apr.2019.06.009
    Buonanno, G., Stabile, L., Avino, P., Belluso, E., 2011. Chemical, dimensional and morphological ultrafine particle characterization from a waste-to-energy plant. Waste Manage. 31(11), 2253-2262. https://doi.org/10.1016/j.wasman.2011.06.017
    Burtscher, H., Schüepp, K., 2012. The occurrence of ultrafine particles in the specific environment of children. Paediatr. Respir. Rev. 13(2), 89-94. https://doi.org/10.1016/j.prrv.2011.07.004
    Buzea, C., Pacheco, I., 2019. 28 - Toxicity of nanoparticles. In: Pacheco-Torgal, F., Diamanti, M.V., Nazari, A., Granqvist, C.G., Pruna, A., Amirkhanian, S. (Eds.), Nanotechnology in Eco-efficient Construction. Woodhead Publishing Series in Civil and Structural Engineering, Cambridge, pp. 705-754. https://doi.org/10.1016/b978-0-08-102641-0.00028-1
    Buzea, C., Pacheco, I.I., Robbie, K., 2007. Nanomaterials and nanoparticles: Sources and toxicity. Biointerphases 2, MR17-MR71. https://doi.org/10.1116/1.2815690
    Bzdek, B.R., Pennington, M.R., Johnston, M.V., 2012. Single particle chemical analysis of ambient ultrafine aerosol: A review. J. Aerosol Sci. 52, 109-120. https://doi.org/10.1016/j.jaerosci.2012.05.001
    Castro-Rodriguez, J.A., Forno, E., Rodriguez-Martinez, C.E., Celedón, J.C., 2016. Risk and Protective Factors for Childhood Asthma: What Is the Evidence? J. Allergy Clin. Immunol.: In Practice 4(6), 1111-1122. https://doi.org/10.1016/j.jaip.2016.05.003
    Cervellati, F., Benedusi, M., Manarini, F., Woodby, B., Russo, M., Valacchi, G., Pietrogrande, M.C., 2020. Proinflammatory properties and oxidative effects of atmospheric particle components in human keratinocytes. Chemosphere 240, 124746. https://doi.org/10.1016/j.chemosphere.2019.124746
    Chen, R., Hu, B., Liu, Y., Xu, J., Yang, G., Xu, D., Chen, C., 2016. Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution. Biochim. Biophys. Acta (BBA), General Subjects 1860(12), 2844-2855. https://doi.org/10.1016/j.bbagen.2016.03.019
    Chen, C., Zhao, Y., Zhang, Y., Zhao, B., 2017. Source strength of ultrafine and fine particle due to Chinese cooking. Procedia Eng. 205, 2231-2237. https://doi.org/10.1016/j.proeng.2017.10.062
    Chen, Q.Y., DesMarais, T., Costa, M., 2019. Metals and mechanisms of carcinogénesis. Annu. Rev. Pharmacol. Toxicol. 59, 537-554. https://10.1146/annurev-pharmtox-010818-021031
    Chen, X.C., Cao, J.J., Ward, T.J., Tian, L.W., Ning, Z., Kumar, N.G., Aquilina, N.J., Lam, S.H.Y., Qu, L., Ho, K.F., 2020. Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong. Sci. Total Environ. 742, 140501. https://doi.org/10.1016/j.scitotenv.2020.140501
    Cheng, Z., Liang, X., Liang, S., Yin, N., Faiola, F., 2020. A human embryonic stem cell-based in vitro model revealed that ultrafine carbon particles may cause skin inflammation and psoriasis. J. Environ. Sci 87, 194-204. https://doi.org/10.1016/j.jes.2019.06.016
    Chu, B., Matti Kerminen, V., Bianchi, F., Yan, C., Petäjä, T., Kulmala, M., 2019. Atmospheric new particle formation in China. Atmos. Chem. Phys. 19(1), 115-138. https://doi.org/10.5194/acp-19-115-2019
    Chung, M.C., Tsai, M.H., Que, D.E., Bongo, S.J., Hsu, W.L., Tayo, L.L., Lin, Y.H., Lin, S.L., Gou, Y.Y., Hsu, Y.C., Hou, W.C., Huang, K.L., Chao, H.R., 2019. Fine particulate matter-induced toxic effects in an animal model of caenorhabditis elegans. Aerosol Air Qual. Res. 19(5), 1068-1078. https://doi.org/10.4209/aaqr.2019.03.0127
    Civeira, M., Pinheiro, R., Gredilla, A., De Vallejuelo, S., Oliveira, M., Ramos, C., Taffarel, S., Kautzmann, R., Madariaga, J., Silva, L.F. (2016). The properties of the nano-minerals and hazardous elements: potential environmental impacts of brazilian coal waste fire. Sci. Total Environ. 544, 892-900. https://doi.org/10.1016/j.scitotenv.2015.12.026
    Clifford, S., Mazaheri, M., Salimi, F., Ezz, W.N., Yeganeh, B., Low-Choy, S., Walker, K., Mengersen, K., Marks, G., Morawska, L., 2018. Effects of exposure to ambient ultrafine particles on respiratory health and systemic inflammation in children. Environ. Int. 114, 167-180. https://doi.org/10.1016/j.envint.2018.02.019
    Cory-Slechta, D.A., Allen, J.L., Conrad, K., Marvin, E., Sobolewski, M., 2018. Developmental exposure to low level ambient ultrafine particle air pollution and cognitive dysfunction. NeuroToxicology 69, 217-231. https://doi.org/10.1016/j.neuro.2017.12.003
    Crobeddu, B., Aragao-Santiago, L., Bui, L.C., Boland, S., Baeza, A.S., 2017. Oxidative potential of particulate matter 2.5 as predictive indicator of cellular. Environ. Pollut. 230, 125-133. https://doi.org/10.1016/j.envpol.2017.06.051
    Cui, J., Halbrook, R.S., Zang, S., Han, S., Li, X., 2018. Metal concentrations in homing pigeon lung tissue as a biomonitor of atmospheric pollution. Ecotoxicology 27(2), 169-174. https://doi.org/10.1007/s10646-017-1882-4
    Cutruneo, C. M. N. L., Oliveira, M. L.S., Ward, C. R., Hower, J. C., de Brum, I.A.S., Sampaio, C.H., Kautzmann, R.M., Taffarel, S. R., Teixeira, E.C., Silva, L.F.O. 2014. A mineralogical and geochemical study of three Brazilian coal cleaning rejects: Demonstration of electron beam applications. Int. J. Coal Geol. 130, 33-52. https://doi.org/10.1016/j.coal.2014.05.009
    Da Costa e Oliveira, J.R., Base, L.H., de Abreu, L.C., Filho, C.F., Ferreira, C., Morawska, L., 2019. Ultrafine particles and children’s health: Literature review. Paediatr. Respir. Rev. 32, 73-81. https://doi.org/10.1016/j.prrv.2019.06.003
    Dall’Osto, M., Thorpe, A., Beddows, D.C.S., Harrison, R.M., Barlow, J.F., Dunbar, T., Williams, P.I., Coe, H., 2011. Remarkable dynamics of nanoparticles in the urban atmosphere. Atmos. Chem. Phys. 11(13), 6623-6637. https://doi.org/10.5194/acp-11-6623-2011
    Dalmora, A.C., Ramos, C.G., Querol, X., Kautzmann, R.M., Oliveira, M.L.S., Taffarel, S.R., Moreno, T., Silva, L.F.O. 2016. Nanoparticulate mineral matter from basalt dust wastes. Chemosphere (Oxford) 144, p. 2013-2017. https://doi.org/10.1016/j.chemosphere.2015.10.047
    De Kok, T.M.C.M., Driece, H.A.L., Hogervorst, J.G.F., Briedé, J.J., 2006. Toxicological assessment of ambient and traffic-related particulate matter: a review of recent studies. Mutat. Res. Rev. Mutat. Res. 613(2-3), 103-122. https://doi.org/10.1016/j.mrrev.2006.07.001
    AQEG, 2017. Ultrafine Particles (UFP) in the UK. Air Quality Expert Group (AQEG). Department for Environment, Food and Rural Affairs; Scottish Government; Welsh Government; and Department of the Environment in Northern Ireland. https://uk-air.defra.gov.uk/assets/documents/reports/cat09/1807261113_180703_UFP_Report_FINAL_for_publication.pdf (accessed 30 December 2020).
    De Oliveira Galvão, M.F., de Oliveira Alves, N., Ferreira, P.A., Caumo, S., de Castro Vasconcellos, P., Artaxo, P., de Souza Hacon, S., Roubicek, D.A., Batistuzzo de Medeiros, S.R., 2018. Biomass burning particles in the Brazilian Amazon region: Mutagenic effects of nitro and oxy-PAHs and assessment of health risks. Environ. Pollut. 233, 960970, https://doi.org/https://doi.org/10.1016/j.envpol.2017.09.068.
    De Roma, A. Neola, B., Serpe, F.P., Sansone, D., Picazio, G., Cerino, P., Esposito, M., 2017. Land Snails (Helix aspersa) as Bioindicators of Trace Element Contamination in Campania (Italy). O. A. Lib. Journal 4(2), e3339. https://doi.org/10.4236/oalib.1103339
    De Vallejuelo, S. F. O., Gredilla, A., da Boit, K., Teixeira, E. C., Sampaio, C. H., Madariaga, J. M., Silva, L. F., 2017. Nanominerals and potentially hazardous elements from coal cleaning rejects of abandoned mines: Environmental impact and risk assessment. Chemosphere, 169, 725-733. https://doi.org/10.1016/j.chemosphere.2016.09.125
    Dias, C. L., Oliveira, M.L.S., Hower, J.C., Taffarel, S.R., Kautzmann, R.M., Silva, L.F.O., 2014. Nanominerals and ultrafine particles from coal fires from Santa Catarina, South Brazil. Int. J. Coal Geol. 122, 50-60. https://doi.org/10.1016/j.coal.2013.12.011
    Donaldson, K., Stone, V., Clouter, A., Renwick, L., Macnee, W., 2001. Ultrafine particles. Occup. Environ. Med. 58, 211-216. https://doi.org/10.1136/oem.58.3.211
    Ehn, M., Thornton J.A., Kleist E., Sipilä, M., Junninen, H., Pullinen, I., Springer, M., Rubach, F., Tillmann, R., Lee, B., Lopez-Hilfiker, F., Andres, S., Acir, I.H., Rissanen, M., Jokinen, T., Schobesberger, S., Kangasluoma, J., Kontkanen, J., Nieminen, T., Kurtén, T., Nielsen, L.B., Jørgensen, S., Kjaergaard, H.G., Canagaratna, M., Maso, M.D., Berndt, T., Petäjä, T., Wahner, A., Kerminen, V.M., Kulmala, M., Worsnop, D.R., Wildt, J., Mentel, T.F. 2014. A large source of low-volatility secondary organic aerosol. Nature. 506, 476-479. https://ezproxy.cuc.edu.co:2067/10.1038/nature13032
    Feng, B., Li, L., Xu, H., Wang, T., Wu, R., Chen, J., Zhang, Y., Liu, S., Ho, S.S.H., Huang, W., 2019. PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in Beijing: Seasonal variations, sources, and risk assessment. J. Environ. Sci. 77, 11-19. https://doi.org/10.1016/j.jes.2017.12.025
    Fernández-Camacho, R., Rodríguez, S., de la Rosa, J., Sánchez de la Campa, A.M., Alastuey, A., Querol, X., González-Castanedo, Y., Garcia-Orellana, I., Nava, S., 2012. Ultrafine particle and fine trace metal (As, Cd, Cu, Pb and Zn) pollution episodes induced by industrial emissions in Huelva, SW Spain. Atmos. Environ. 61, 507-517. https://doi.org/10.1016/j.atmosenv.2012.08.003
    Fleischer, N.L., Merialdi, M., van Donkelaar, A., Vadillo-Ortega, F., Martin, R.V., Betran, A.P., Souza, J.P., O’Neill, M. S., 2014. Outdoor air pollution, preterm birth, and low birth weight: Analysis of the world health organization global survey on maternal and perinatal health. Environ. Health Perspect. 122(4), 425-430. https://doi.org/10.1289/ehp.1306837
    Forti, L., Jeuland, N., Raux, S., Pasquereau, M., 2005. Analysis of the particulates emitted by internal combustion engines. Oil Gas Sci. Technol, 60 (6), 995-1011. https://doi.org/10.2516/ogst:2005070
    Gao, R., Sang, N., 2020. Quasi-ultrafine particles promote cell metastasis via HMGB1-mediated cancer cell adhesion. Environ. Pollut. 256, 113390. https://doi.org/10.1016/j.envpol.2019.113390
    Gao, D., Ripley, S., Weichenthal, S., Godri Pollitt, K.J., 2020. Ambient particulate matter oxidative potential: Chemical determinants, associated health effects, and strategies for risk management. Free Radic. Biol. Med. 151, 7-25. https://doi.org/10.1016/j.freeradbiomed.2020.04.028
    Garcia, K.O., Teixeira, E.C., Agudelo-Castañeda, D. M., Braga, M., Alabarse, P. G., Wiegand, F., Kautzmann, R.M., Silva, L.F. (2014). Assessment of nitro-polycyclic aromatic hydrocarbons in pm1 near an area of heavy-duty traffic. Sci. Total Environ. 479-480, 57-65. https://doi.org/10.1016/j.scitotenv.2014.01.126
    Gasparotto J., Chaves, P.R., Da Boit M.K., Da Rosa-Siva H., Bortolin R., Silva L.F.O., Rabelo T., Da Silva J., Da Silva F., Nordin A., Soares K., Borges M., Gelain D., Moreira J. 2018. Obese rats are more vulnerable to inflammation, genotoxicity and oxidative stress induced by coal dust inhalation than non-obese rats. Ecotoxicol. Environ. Saf., 165, 44-51. https://doi.org/10.1016/j.ecoenv.2018.08.097
    Gasparotto, J., Da Boit M.K., 2021. Coal as an energy source and its impacts on human health. Energy Geoscience. https://doi.org/10.1016/j.engeos.2020.07.003
    Gasparotto, J., Rodrigues, C.P., Da Boit, M.K., Silva O.L.F., Gelain, D.P., Fonseca, M.J.C. 2019. Obesity associated with coal ash inhalation triggers systemic inflammation and oxidative damage in the hippocampus of rats. Food Chem. Toxicol. 133, 110766. https://doi.org/10.1016/j.fct.2019.110766
    Goel, A., Kumar, P., 2015. Characterisation of nanoparticle emissions and exposure at traffic intersections through fast-response mobile and sequential measurements. Atmos. Environ. 107, 374-390. https://doi.org/10.1016/j.atmosenv.2015.02.002
    Gómez-Ugalde, R., 2003. Efectos de la contaminación atmosférica en poblaciones de pequeños roedores silvestres (Microtus mexicanus, Peromyscus Melanotis y Peromiscus Difficilis) en México, D. F. Ph.D. Thesis, Universitat de Barcelona, 415 pp. https://core.ac.uk/download/pdf/19919452.pdf
    González, L.T., Longoria Rodríguez, F.E., Sánchez-Domínguez, M., Cavazos, A., Leyva-Porras, C., Silva-Vidaurri, L. G., Acuña Askar, K., Kharissov, B.I., Villareal Chiu, J.F., Alfaro Barbosa, J.M., 2017. Determination of trace metals in TSP and PM2.5 materials collected in the Metropolitan Area of Monterrey, Mexico: A characterization study by XPS, ICP-AES and SEM-EDS. Atmos. Res. 196, 8-22. https://doi.org/10.1016/j.atmosres.2017.05.009
    Gonzalez-Moragas, L., Roig, A., Laromaine, A., 2015. C. elegans as a tool for in vivo nanoparticle assessment. Adv. Colloid Interface Sci. 219, 10-26. https://doi.org/10.1016/j.cis.2015.02.001
    Grana, M., Toschi, N., Vicentini, L., Pietroiusti, A., Magrini, A., 2017. Exposure to ultrafine particles in different transport modes in the city of Rome. Environ. Pollut. 228, 201-210. https://doi.org/10.1016/j.envpol.2017.05.032
    Guo, L., Johnson, G.R., Hofmann, W., Wang, H., Morawska, L., 2019. Deposition of ambient ultrafine particles in the respiratory tract of children: a novel experimental method and its application. J. Aerosol Sci. 139, 105465. https://doi.org/10.1016/j.jaerosci.2019.105465
    Habre, R., Zhou, H., Eckel, S. P., Enebish, T., Fruin, S., Bastain, T., Rappatort, E., Gilliland, F., 2018. Short-term effects of airport-associated ultrafine particle exposure on lung function and inflammation in adults with asthma. Environ. Int. 118, 48-59. https://doi.org/10.1016/j.envint.2018.05.031
    HEI, 2013. Understanding the Health Effects of Ambient Ultrafine Particles. HEI Review Panel on Ultrafine Particles. HEI Perspectives 3. Health Effects Institute (HEI). https://www.healtheffects.org/system/files/Perspectives3.pdf (accessed 04 October 2020)
    Heusinkveld, H.J., Wahle, T., Campbell, A., Westerink, R.H.S., Tran, L., Johnston, H., Stone, V., Cassee, F.R., Schins, R.P.F., 2016. Neurodegenerative and neurological disorders by small inhaled particles. NeuroToxicology 56, 94-106. https://doi.org/10.1016/j.neuro.2016.07.007
    Hofman, J., Samson, R., Joosen, S., Blust, R., Lenaerts, S., 2018. Cyclist exposure to black carbon, ultrafine particles and heavy metals: An experimental study along two commuting routes near Antwerp, Belgium. Environ. Res. 164, 530-538. https://doi.org/10.1016/j.envres.2018.03.004
    Islam, N., Rabha, S. Silva, L.F.O., Saikia, B. K. 2019. Air quality and PM10-associated poly-aromatic hydrocarbons around the railway traffic area: statistical and air mass trajectory approaches. Environ. Geochem. Health 41, 2039-2053. https://doi.org/10.1007/s10653-019-00256-z
    Jantzen, K., Møller, P., Karottki, D.G., Olsen, Y., Bekö, G., Clausen, G., Hersoug, L.G., Loft, S., 2016. Exposure to ultrafine particles, intracellular production of reactive oxygen species in leukocytes and altered levels of endothelial progenitor cells. Toxicology 359-360, 11-18. https://doi.org/10.1016/j.tox.2016.06.007
    Jeong, C.H., Traub, A., Evans, G.J., 2017. Exposure to ultrafine particles and black carbon in diesel-powered commuter trains. Atmos. Environ. 155, 46-52. https://doi.org/10.1016/j.atmosenv.2017.02.015
    De Jesus, A.L., Rahman, M.M., Mazaheri, M., Thompson, H., Knibbs, L.D., Jeong, C., Evans, G., Nei, W., Ding, A., Liping, Q., Li, L., Portin, H., Niemi, J.V., Timonen, H., Luoma, K., Petäjä, T., Kulmala, M., Kowalski, M., Peters, A., Cyrys, J., Ferrero, L., Manigrasso, M., Avino, P., Buonano, G., Reche, C., Querol, X., Beddows, D., Harrison, R.M., Sowlat, M.H., Sioutas, C., Morawska, L., 2019. Ultrafine particles and PM2.5 in the air of cities around the world: Are they representative of each other? Environ. Int. 129, 118-135. https://doi.org/10.1016/j.envint.2019.05.021
    Jones, A.M., Harrison, R.M., 2016. Emission of ultrafine particles from the incineration of municipal solid waste: A review. Atmos. Environ. 140, 519-528. https://doi.org/10.1016/j.atmosenv.2016.06.005
    Kecorius, S., Kivekäs, N., Kristensson, A., Tuch, T., Covert, D.S., Birmili, W., Lihavainen, H., Hyvärinen, A.P., Martinsson, J., Sporre, M.K., Swietlicki, E. Wiedensohler, A., Ulevicius, V., 2016. Significant increase of aerosol number concentrations in air masses crossing a densely trafficked sea area. Oceanologia 58(1), 1-12. https://doi.org/10.1016/j.oceano.2015.08.001
    Kelly, F.J., Fussell, J.C., 2012. Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter. Atmos. Environ. 60, 504-526. https://doi.org/10.1016/j.atmosenv.2012.06.039
    Keuken, M.P., Moerman, M., Zandveld, P., Henzing, J.S., 2015. Total and size-resolved particle number and black carbon concentrations near an industrial area. Atmos. Environ. 122, 196-205. https://doi.org/10.1016/j.atmosenv.2015.09.047
    Kim, K.H.H., Jahan, S.A., Kabir, E., Brown, R.J.C.C., 2013. A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects. Environ. Int. 60, 71-80. https://doi.org/10.1016/j.envint.2013.07.019
    Kim, H.L., Han, J., Lee, S.M., Kwon, H.B., Hwang, J., Kim, Y.J., 2018. MEMS-based particle detection system for measuring airborne ultrafine particles. Sens. Actuator A. Phys. 283, 235-244. https://doi.org/10.1016/j.sna.2018.09.060
    Klaassen, C. D., 2013. Casarett and Doull’s: Toxicology, The basic science of poison. Eighth Edition. Mc Graw Hill Education – Medical, 525-907. USA. ISBN: 978-0-07-176922-8
    Koçak, M., Mihalopoulos, N., Kubilay, N., 2007. Contributions of natural sources to high PM10 and PM2.5 events in the eastern Mediterranean. Atmos. Environ. 41(18), 3806-3818. https://doi.org/10.1016/j.atmosenv.2007.01.009
    Kumar, P., Robins, A., Vardoulakis, S., Britter, R., 2010. A review of the characteristics of nanoparticles in the urban atmosphere and the prospects for developing regulatory controls. Atmos. Environ. 44(39), 5035-5052. https://doi.org/10.1016/j.atmosenv.2010.08.016
    Kronbauer, M.A., Izquierdo, M., Dai, S., Wannders, F.B., Wagner, N.J., Mastalerz, M., Hower, J.C., Oliverira, M.L.S., Taffarel, S.R., Bizani, D., Silva, L.F.O., 2013. Geochemistry of ultra-fine and nano-compounds in coal gasification ashes: A synoptic view. Science of the Total Environment 456-457, 95–103. https://doi.org/10.1016/j.scitotenv.2013.02.066
    Kumar, P., Ketzel, M., Vardoulakis, S., Pirjola, L., Britter, R., 2011. Dynamics and dispersion modelling of nanoparticles from road traffic in the urban atmospheric environment-A review. J. Aerosol Sci. 42(9), 580-603. https://doi.org/10.1016/j.jaerosci.2011.06.001
    Kumar, P., Morawska, L., Birmili, W., Paasonen, P., Hu, M., Kulmala, M., Harrison, R.M., Norford, L., Britter, R., 2014. Ultrafine particles in cities. Environment International 66, 1-10. https://doi.org/10.1016/j.envint.2014.01.013
    Kumar, P., Wiedensohler, A., Birmili, W., Quincey, P., Hallquist, M., 2016. Ultrafine Particles Pollution and Measurements. Compr. Anal. Chem. 73, 369-390. https://doi.org/10.1016/bs.coac.2016.04.004
    Kumar, P., Patton, A.P., Durant, J.L., Frey, H.C., 2018. A review of factors impacting exposure to PM2.5, ultrafine particles and black carbon in Asian transport microenvironments. Atmos. Environ. 187, 301-316. https://doi.org/10.1016/j.atmosenv.2018.05.046
    Kwon, H.S., Ryu, M.H., Carlsten, C., 2020. Ultrafine particles: unique physicochemical properties relevant to health and disease. Exp. Mol. Med. 52(3), 318-328. https://doi.org/10.1038/s12276-020-0405-1
    Landkocz, Y., Ledoux, F., André, V., Cazier, F., Genevray, P., Dewaele, D., Martin, P.J., Lepers, C., Verdin, A., Courcot, L., Boushina, S., Sichel, F., Gualtieri, M., Shirali, P., Courcot, D., Billet, S., 2017. Fine and ultrafine atmospheric particulate matter at a multi-influenced urban site: Physicochemical characterization, mutagenicity and cytotoxicity. Environ. Pollut. 221, 130-140. https://doi.org/10.1016/j.envpol.2016.11.054
    Lanzinger, S., Schneider, A., Breitner, S., Stafoggia, M., Erzen, I., Dostal, M., Pastorkova, A., Bastian, S., Cyrys, J., Zscheppang, A., Kolodnitska, T., Peters, A., Mykhalchuk, B. (2016). Associations between ultrafine and fine particles and mortality in five central European cities - Results from the UFIREG study. Environ. Int. 88, 44-52. https://doi.org/10.1016/j.envint.2015.12.006
    Lavigne, E., Lima, I., Hatzopoulou, M., Van Ryswyk, K., Decou, M.L., Luo, W., van Donkelaar, A., Martin, R.V., Chen, H., Stieb, D.M., Crighton, E., Gasparrini, A., Elten, M., Yasseen III, A.S., Burnett, R.T., Walker, M., Weichenthal, S., 2019. Spatial variations in ambient ultrafine particle concentrations and risk of congenital heart defects. Environ. Int. 130, 104953. https://doi.org/10.1016/j.envint.2019.104953
    Lee, W., Bell, M.L., Gasparrini, A., Armstrong, B.G., Sera, F., Hwang, S., Lavigne, E., Zanobetti, A., Coelho, M.S.Z.S., Saldiva, P.H.N., Osorio, S., Tobias, A., Zeka, A., Goodman, P.G., Forsberg, B., Rocklöv, J., Hashizume, M., Honda, Y., Guo, Y.L.L., Seposo, X., Dung, D.V., Dang, T.N., Tong, S., Guo, Y., Kim, H., 2017. Mortality burden of diurnal temperature range and its temporal changes : A multi-country study. Environ. Int. 110, 123-130. https://doi.org/10.1016/j.envint.2017.10.018
    León-Mejía, G., Silva, L.F., Civeira, M.S., Oliveira, M.L.S., Machado, M., Villela, I.V., Hartmann, A., Premoli, S., Corrêa, D.S., Silva, L., Henriques, J.A.P., 2016. Cytotoxicity and genotoxicity induced by coal and coal fly ash particles samples in V79 cells, Environ. Sci. Pollut. Res., 23, 24019-24031. https://ezproxy.cuc.edu.co:2067/10.1007/s11356-016-7623-z
    León-Mejía, G., Machado, M.N., Okuro, R.T., Silva, L.F., Telles, C., Dias, J., Niekraszewicz, L., Da Silva, J., Henriques, J.A.P., Zin, W.A., 2018. Intratracheal instillation of coal and coal fly ash particles in mice induces DNA damage and translocation of metals to extrapulmonary tissues. Sci. Total Environ. 625, 589-599. https://doi.org/10.1016/j.scitotenv.2017.12.283
    Li, Y., Yang, M., Meng, T., Niu, Y., Dai, Y., Zhang, L., Zheng, X., Jalava, P., Dong, G., Gao, W., Zheng, Y., 2020. Oxidative stress induced by ultrafine carbon black particles can elicit apoptosis in vivo and vitro. Sci. Total Environ. 709, 135802. https://doi.org/10.1016/j.scitotenv.2019.135802
    Liati, A., Schreiber, D., Arroyo Rojas Dasilva, Y., Dimopoulos Eggenschwiler, P., 2018. Ultrafine particle emissions from modern Gasoline and Diesel vehicles: An electron microscopic perspective. Environ. Pollut. 239, 661-669. https://doi.org/10.1016/j.envpol.2018.04.081
    Liu, J.Y., Hsiao, T.C., Lee, K.Y., Chuang, H.C., Cheng, T.J., Chuang, K.J., 2018. Association of ultrafine particles with cardiopulmonary health among adult subjects in the urban areas of northern Taiwan. Sci. Total Environ. 627, 211-215. https://doi.org/10.1016/j.scitotenv.2018.01.218
    Lopes, M., Russo, A., Monjardino, J., Gouveia, C., Ferreira, F., 2019. Monitoring of ultrafine particles in the surrounding urban area of a civilian airport. Atmos. Pollut. Res. 10(5), 1454-1463. https://doi.org/10.1016/j.apr.2019.04.002
    Louis, C., Liu, Y., Tassel, P., Perret, P., Chaumond, A., André, M., 2016. PAH, BTEX, carbonyl compound, black-carbon, NO2 and ultrafine particle dynamometer bench emissions for Euro 4 and Euro 5 diesel and gasoline passenger cars. Atmos. Environ. 141, 80-95. https://doi.org/10.1016/j.atmosenv.2016.06.055
    Lü, S., Zhang, R., Yao, Z., Yi, F., Ren, J., Wu, M., Feng, M., Wang, Q., 2012. Size distribution of chemical elements and their source apportionment in ambient coarse, fine, and ultrafine particles in Shanghai urban summer atmosphere. J. Environ. Sci. 24(5), 882-890. https://doi.org/10.1016/S1001-0742(11)60870-X
    Lü, S., Hao, X., Liu, D., Wang, Q.Q., Zhang, W., Liu, P. Zhang, R., Yu, S., Pan, R., Wu, M., Yonemochi, S., Wang, Q., 2016. Mineralogical characterization of ambient fine/ultrafine particles emitted from Xuanwei C1 coal combustion. Atmos. Res. 169, 17-23. https://doi.org/10.1016/j.atmosres.2015.09.020
    Luengo-Oroz, J., Reis, S., 2019. Assessment of cyclists’ exposure to ultrafine particles along alternative commuting routes in Edinburgh. Atmos. Pollut. Res. 10(4), 1148-1158. https://doi.org/10.1016/j.apr.2019.01.020
    Lundborg, M., Johard, U., Låstbom, L., Gerde, P., Camner, P., 2001. Human alveolar macrophage phagocytic function is impaired by aggregates of ultrafine carbon particles. Environ. Res. 86(3), 244-253. https://doi.org/10.1006/enrs.2001.4269
    Ma, N., Birmili, W., 2015. Estimating the contribution of photochemical particle formation to ultrafine particle number averages in an urban atmosphere. Sci Total Environ. 512-513, 154-166. https://doi.org/10.1016/j.scitotenv.2015.01.009
    Magalhaes, S., Baumgartner, J., Weichenthal, S., 2018. Impacts of exposure to black carbon, elemental carbon, and ultrafine particles from indoor and outdoor sources on blood pressure in adults: A review of epidemiological evidence. Environ. Res. 161, 345-353. https://doi.org/10.1016/j.envres.2017.11.030
    Maji, S., Ahmed, S., Siddiqui, W.A., Ghosh, S., 2017. Short term effects of criteria air pollutants on daily mortality in Delhi, India. Atmos. Environ. 150, 210-219. https://doi.org/10.1016/j.atmosenv.2016.11.044
    Marabini, L., Ozgen, S., Turacchi, S., Aminti, S., Arnaboldi, F., Lonati, G., Fermo, P., Corbella, L., Valli, G., Bernardoni, V., Dell’Acqua, M., Vecchi, R., Becagli, S., Caruso, D., Corrado, G.L., Marinovich, M., 2017. Ultrafine particles (UFPs) from domestic wood stoves: genotoxicity in human lung carcinoma A549 cells. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 820, 39-46. https://doi.org/10.1016/j.mrgentox.2017.06.001
    Marimon-Bolívar, W., Tejeda-Benítez, L.P., Núñez-Avilés, C.A., De Léon-Pérez, D.D., 2019. Evaluation of the in vivo toxicity of green magnetic nanoparticles using Caenorhabditis elegans as a biological model. Environ. Nanotechnol. Monit. Manag. 12, 100253. https://doi.org/10.1016/j.enmm.2019.100253
    Martinello, K., Oliveira, M., Molossi, F., Ramos, C., Teixeira, E., Kautzmann, R., Silva, L.F., 2014. Direct identification of hazardous elements in ultra-fine and nanominerals from coal fly ash produced during diesel co-firing. Sci. Total Environ. 470-471, 444-452. https://doi.org/10.1016/j.scitotenv.2013.10.007
    Martins, V., Correia, C., Cunha-Lopes, I., Faria, T., Diapouli, E., Manousakas, M.I., Eleftheriadis, K., Almeida, S.M. 2021. Chemical characterisation of particulate matter in urban transport modes. J. Environ. Sci. 100, 51-61. https://doi.org/10.1016/j.jes.2020.07.008
    Miller, B. G., 2011. 9 - Emissions Control Strategies for Power Plants. In: Miller, B.G. (Ed.), Clean Coal Engineering Technology. Elsevier, Amsterdam, pp. 375-481. https://doi.org/10.1016/b978-1-85617-710-8.00009-1
    Miller, M.R., Shaw, C.A., Langrish, J.P., 2012. From particles to patients: Oxidative stress and the cardiovascular effects of air pollution. Future Cardiol. 8(4), 577-602. https://doi.org/10.2217/fca.12.43
    Mishra, R.K., Shukla, A., Parida, M., Pandey, G., 2016. Urban roadside monitoring and prediction of CO, NO2 and SO2 dispersion from on-road vehicles in megacity Delhi. Transp. Res. D Transp. Environ. 46, 157-165. https://doi.org/10.1016/j.trd.2016.03.019
    Møller, K.L., Brauer, C., Mikkelsen, S., Bonde, J.P., Loft, S., Helweg-Larsen, K., Thygesen, L. C., 2020. Cardiovascular disease and long-term occupational exposure to ultrafine particles: A cohort study of airport workers. Int. J. Hyg. Environ. Health 223(1), 214-219. https://doi.org/10.1016/j.ijheh.2019.08.010
    Morawska, L., Ristovski, Z., Jayaratne, E.R., Keogh, D.U., Ling, X., 2008. Ambient nano and ultrafine particles from motor vehicle emissions: Characteristics, ambient processing and implications on human exposure. Atmos. Environ. 42(35), 8113-8138. https://doi.org/10.1016/j.atmosenv.2008.07.050
    Morris-Schaffer, K., Sobolewski, M., Welle, K., Conrad, K., Yee, M., O’Reilly, M.A., Cory-Slechta, D.A., 2018. Cognitive flexibility deficits in male mice exposed to neonatal hyperoxia followed by concentrated ambient ultrafine particles. Neurotoxicol. Teratol. 70, 51-59. https://doi.org/10.1016/j.ntt.2018.10.003
    Muñoz-Salazar, J.I., Raga, G.B., Yakobi-Hancock, J., Kim, J.S., Rosas, D., Caudillo, L., Alvarez-Ospina, H., Ladino, L.A., 2020. Ultrafine aerosol particles in the western Caribbean: A first case study in Merida. Atmos. Pollut. Res. 11(10), 1767-1775. https://doi.org/10.1016/j.apr.2020.07.008
    Nho, R., 2020. Pathological effects of nano-sized particles on the respiratory system. Nanomedicine : N. B.M. 29, 102242. https://doi.org/10.1016/j.nano.2020.102242
    Nyarku, M., Buonanno, G., Ofosu, F., Jayaratne, R., Mazaheri, M., Morawska, L., 2019. Schoolchildren’s personal exposure to ultrafine particles in and near Accra, Ghana. Environ. Int. 133. https://doi.org/10.1016/j.envint.2019.105223
    Oberdörster, G., Sharp, Z., Atudorei, V., Elder, A., Gelein, R., Lunts, A., Kreyling, W., Cox, C., 2002. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J. Toxicol. Environ. Health Part A. 65(20), 1531-1543. https://doi.org/10.1080/00984100290071658
    Ohlwein, S., Kappeler, R., Kutlar Joss, M., Künzli, N., Hoffmann, B., 2019. Health effects of ultrafine particles: a systematic literature review update of epidemiological evidence. Int. J. Public Health 64, 547-449. https://doi.org/10.1007/s00038-019-01202-7
    Oliveira, M. L.S., Navarro, O. G., Crissien, T.J., Tutikian, B.F., Da Boit, K., Texeira, E.C., Cabello, J.J., Agudelo-Castañeda, D. M., Silva, L.F.O., 2017. Coal emissions adverse human health effects associated with ultrafine/nano-particles role and resultant engineering controls. Environ. Res., 158, 450-455. https://doi.org/10.1016/j.envres.2017.07.002
    Oliveira, M.L.S., Izquierdo, M., Querol, X., Lieberman, R.N., Saikia, B.K., Silva, L.FO. 2019a. Nanoparticles from Construction Wastes: A Problem to Health and the Environment. J. Clean. Prod. 219, 236-243. https://doi.org/10.1016/j.jclepro.2019.02.096
    Oliveira, M.L.S., Pinto, D., Tutikian, B.F., Da Boit, K., Saikia, B.K., Silva, L.F.O., 2019b. Pollution from uncontrolled coal fires: Continuous gaseous emissions and nanoparticles from coal mining industry. J. Clean. Prod. 215, 1140-1148. https://doi.org/10.1016/j.jclepro.2019.01.169
    Paunescu, A.C., Casas, M., Ferrero, A., Pañella, P., Bougas, N., Beydon, N., Just, J., Lezmi, J., Ballester, F., Momas, I., 2019. Associations of black carbon with lung function and airway inflammation in schoolchildren. Environ. Int. 131, 104984. https://doi.org/10.1016/j.envint.2019.104984
    Peralta, O., Ortínez-Alvarez, A., Basaldud, R., Santiago, N., Alvarez-Ospina, H., de la Cruz, K., Barrera, V., Espinosa, M.D.L.C., Saavedra, I., Castro, T., Martínez-Arroyo, A., Páramo, V.H., Ruíz-Suárez, L.G., Vazquez-Galvez, F.A., Gavilán, A., 2019. Atmospheric black carbon concentrations in Mexico. Atmos. Res. 230, 104626. https://doi.org/10.1016/j.atmosres.2019.104626
    Pétursdóttir, U., Kirkelund, G.M., Press-Kristensen, K., Hertel, O., Mikkelsen, T.N., 2018. Ultrafine particles in inhabited areas in the Arctic - From very low to high concentrations. Atmos. Pollut. Res. 9(2), 299-308. https://doi.org/10.1016/j.apr.2017.10.008
    Platel, A., Privat, K., Talahari, S., Delobel, A., Dourdin, G., Gateau, E., Simar, S., Saleh, Y., Sotty, J., Antherieu, S., Canivet, L., Alleman, L.Y., Perdrix, E., Garçon, G., Denayer, F.O., Lo Guidice, J.M., Nesslany, F., 2020. Study of in vitro and in vivo genotoxic effects of air pollution fine (PM2.5-0.18) and quasi-ultrafine (PM0.18) particles on lung models. Sci. Total Environ. 711, 134666. https://doi.org/10.1016/j.scitotenv.2019.134666
    Pourret, O., Hursthouse, A., 2019. It’s time to replace the term “heavy metals” with “potentially toxic elements” when reporting environmental research. Int. J. Environ. Res. Public Health 16 (22), 4446. https://doi.org/10.3390/ijerph16224446
    Pyo, J., Ock, Y., Jeong, D., Park, K., Lee, D., 2017. Development of filter-free particle filtration unit utilizing condensational growth: With special emphasis on high-concentration of ultrafine particles. Build. Environ. 112, 200-208. https://doi.org/10.1016/j.buildenv.2016.11.011
    Ramírez, O., Sánchez de la C.A.M., Amato F., Moreno, T., Silva L.F.O, and de la Rosa J. 2019. Physicochemical Characterization and Sources of the Thoracic Fraction of Road Dust in a Latin American Megacity. Sci. Total Environ. 652, 434–46. https://doi.org/10.1016/j.scitotenv.2018.10.214
    Ramírez, O., Da Boit, K., Blanco, E., Silva, L.F.O., 2020. Hazardous thoracic and ultrafine particles from road dust in a Caribbean industrial city. Urban Clim. 33, 100655. https://doi.org/10.1016/j.uclim.2020.100655
    Rengarajan, T., Rajendran, P., Nandakumar, N., Lokeshkumar, B., Rajendran, P., Nishigaki, I., 2015. Exposure to polycyclic aromatic hydrocarbons with special focus on cancer. Asian Pac. J. Trop. Biomed. 5, 182-189. https://doi.org/10.1016/S2221-1691(15)30003-4
    Ribeiro, J., and Flores, D., 2020. Occurrence, leaching and mobility of trace elements in a coal mining waste dump: the case of Douro Coalfield (Portugal). Energy Geoscience, https://doi.org/10.1016/j.engeos.2020.09.005
    Ribeiro, J., Daboit, K., Flores, D., Kronbauer, M.A., Silva, L.F.O. 2013a. Extensive FE-SEM/EDS, HR-TEM/EDS and ToF-SIMS studies of micron- to nano-particles in anthracite fly ash. Sci. Total Environ. 452-453, 98-107. https://doi.org/10.1016/j.scitotenv.2013.02.010
    Ribeiro, J., Taffarel, S.R., Sampaio, C.H., Flores, D., Silva, L.F.O., 2013b. Mineral speciation and fate of some hazardous contaminants in coal waste pile from anthracite mining in Portugal. Int. J. Coal Geol. 109-110, 15-23. https://doi.org/10.1016/j.coal.2013.01.007
    Rizza, V., Stabile, L., Vistocco, D., Russi, A., Pardi, S., Buonanno, G., 2019. Effects of the exposure to ultrafine particles on heart rate in a healthy population. Sci. Total Environ. 650, 2403-2410. https://doi.org/10.1016/j.scitotenv.2018.09.385
    Rojas, J.C., Sánchez, N.E., Schneider, I., Teixeira, E.C., Silva, L.F.O., 2019. Exposure to nanometric pollutants in primary schools: Environmental implications. Urban Clim. 27, 412-419. https://doi.org/10.1016/j.uclim.2018.12.011
    Sade, M.Y., Novack, V., Ifergane, G., Horev, A., Kloog, I., 2015. Air pollution and ischemic stroke among young adults. Stroke 46(12), 3348-3353. https://doi.org/10.1161/STROKEAHA.115.010992
    Saha, P.K., Zimmerman, N., Malings, C., Hauryliuk, A., Li, Z., Snell, L., Subramanian, R., Lipsky, E., Apte, J.S., Robinson, A.L., Presto, A.A., 2019. Quantifying high-resolution spatial variations and local source impacts of urban ultrafine particle concentrations. Sci. Total Environ. 655, 473-481. https://doi.org/10.1016/j.scitotenv.2018.11.197
    Saikia, B.K., Saikia, J., Rabha, S., Silva, L.F.O., Finkelman, R., 2018. Ambient nanoparticles/nanominerals and hazardous elements from coal combustion activity: Implications on energy challenges and health hazards. Geosci. Front. 9(3), 863-875. https://doi.org/10.1016/j.gsf.2017.11.013
    Sanderson, P., Delgado-Saborit, J.M., Harrison, R.M., 2014. A review of chemical and physical characterisation of atmospheric metallic nanoparticles. Atmos. Environ. 94, 353-365. https://doi.org/10.1016/j.atmosenv.2014.05.023
    Santibáñez-Andrade, M., Quezada-Maldonado, E.M., Osornio-Vargas, Á., Sánchez-Pérez, Y., García-Cuellar, C.M., 2017. Air pollution and genomic instability: The role of particulate matter in lung carcinogenesis. Environ. Pollut. 229, 412-422. https://doi.org/10.1016/j.envpol.2017.06.019
    Schneider, I.L., Teixeira, E.C., Silva L.F., Wiegand, F. 2015. Atmospheric particle number concentration and size distribution in a traffic-impacted area. Atmos. Pollut. Res. 6, 877-885. https://doi.org/10.5094/APR.2015.097
    Schneider, I.L., Teixeira, E.C., Agudelo-Castañeda, D., Silva e Silva, G., Balzaretti, N., Braga, M., Silva, L.F.O. 2016. FTIR analysis and evaluation of carcinogenic and mutagenic risks of nitro-polycyclic aromatic hydrocarbons in PM1.0. Sci. Total Environ. 541, 1151-1160. https://doi.org/10.1016/j.scitotenv.2015.09.142
    Seigneur, C., 2019. Atmospheric Dispersion. Air Pollution: Concepts, Theory, and Applications. Cambridge University Press, pp. 95-124. https://doi.org/10.1017/9781108674614.006
    Sharma, S., Kumar, M.S., Parmar, A., Sachar, S., 2018. Chapter 18 – Understanding toxicity of nanomaterials in the environment: crucial tread for controlling the production, processing, and assessing the risk. Nanomaterials in Chromatography, pp. 467-500. https://doi.org/10.1016/B978-0-12-812792-6.00018-2
    Shukla, A., Bunkar, N., Kumar, R., Bhargava, A., Tiwari, R., Chaudhury, K., Goryacheva, I.Y., Mishra, P.K., 2019. Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms. Sci. Total Environ. 656, 760-777. https://doi.org/10.1016/j.scitotenv.2018.11.381
    Silva, L.F.O., Da Boit, K., Sampaio, C.H., Jasper, A., Andrade, M.L., Kostova, I.J., Waanders, F.B., Henke, K.R., Hower, J.C. 2012a. The occurrence of hazardous volatile elements and nanoparticles in Bulgarian coal fly ashes and the effect on human health exposure. Sci. Total Environ. 416, 513-526. https://doi.org/10.1016/j.scitotenv.2011.11.012
    Silva, L.F.O., Jasper, A., Andrade, M.L., Sampaio, C.H., Dai, S., Li, X., Li, T., Chen, W., Wang, X., Liu, H., Zhao, L., Hopps, S.G., Jewell, R.F., Hower, J.C. 2012b. Applied investigation on the interaction of hazardous elements binding on ultrafine and nanoparticles in Chinese anthracite-derived fly ash. Sci. Total Environ. 419, 250-264. https://doi.org/10.1016/j.scitotenv.2011.12.069
    Silva, L.F.O., Milanes, C., Pinto, D., Ramirez, O., Lima, B.D. 2020a. Multiple hazardous elements in nanoparticulate matter from a Caribbean industrialized atmosphere. Chemosphere 239, 124776. https://doi.org/10.1016/j.chemosphere.2019.124776
    Silva, L.F.O., Pinto, D., Neckel, A., Oliveira, M.L.S., Sampaio, C.H., 2020b. Atmospheric nanocompounds on Lanzarote Island: Vehicular exhaust and igneous geologic formation interactions. Chemosphere 254, 126822. https://doi.org/10.1016/j.chemosphere.2020.126822
    Simkhovich, B.Z., Kleinman, M.T., Kloner, R.A., 2008. Air Pollution and Cardiovascular Injury: Epidemiology, Toxicology, and Mechanisms. J. Am. Coll. Cardiol. 52(9), 719-726. https://doi.org/10.1016/j.jacc.2008.05.029
    Sinis, S.I., Gourgoulianis, K.I., Hatzoglou, C., Zarogiannis, S.G., 2019. Mechanisms of engineered nanoparticle induced neurotoxicity in Caenorhabditis elegans. Environ. Toxicol. Pharmacol. 67, 29-34. https://doi.org/10.1016/j.etap.2019.01.010
    Slezakova, K., de Oliveira Fernandes, E., Pereira, M.D.C., 2019. Assessment of ultrafine particles in primary schools: Emphasis on different indoor microenvironments. Environ. Pollut. 246, 885-895. https://doi.org/10.1016/j.envpol.2018.12.073
    Song, H., Zhang, Y., Luo, M., Gu, J., Wu, M., Xu, D., Xu, G., Ma, L. 2019. Seasonal variation, sources and health risk assessment of polycyclic aromatic hydrocarbons in different particle fractions of PM2.5 in Beijing, China. Atmos. Pollut. Res. 10(1), 105-114. https://doi.org/10.1016/j.apr.2018.06.012
    Soppa, V.J., Shinnawi, S., Hennig, F., Sasse, B., Hellack, B., Kaminski, H., Quass, U., Schins, R.P.F., Kuhlbusch, T.A.J., Hoffmann, B., 2019. Effects of short-term exposure to fine and ultrafine particles from indoor sources on arterial stiffness – A randomized sham-controlled exposure study. Int. J. Hyg. Environ. Health 222(8), 1115-1132. https://doi.org/10.1016/j.ijheh.2019.08.002
    Srimuruganandam, B., Shiva Nagendra, S.M., 2011. Chemical characterization of PM10 and PM2.5 mass concentrations emitted by heterogeneous traffic. Sci. Total Environ. 409(17), 3144-3157. https://doi.org/10.1016/j.scitotenv.2011.04.042
    Stacey, B., 2019. Measurement of ultrafine particles at airports: A review. Atmos. Environ. 198, 463-477. https://doi.org/10.1016/j.atmosenv.2018.10.041
    Stacey, B., Harrison, R.M., Pope, F., 2020. Evaluation of ultrafine particle concentrations and size distributions at London Heathrow Airport. Atmos. Environ. 222, 117148. https://doi.org/10.1016/j.atmosenv.2019.117148
    Stafoggia, M., Schneider, A., Cyrys, J., Samoli, E., Andersen, Z.J., Bedada, G.B., Bellander, T., Cattani, G., Eleftheriadis, K., Faustini, A., Hoffmann, B., Jacquemin, B., Katsouyanni, K., Massling, A., Pekkanen, J., Perez, N., Peters, A., Quass, U., Yli-Tuomi, T., Forastiere, F., UFandHEALTH Study Group., 2017. Association Between Short-term Exposure to Ultrafine Particles and Mortality in Eight European Urban Areas. Epidemiology 28(2), 172-180. https://doi.org/10.1097/EDE.0000000000000599
    Sun, J., Birmili, W., Hermann, M., Tuch, T., Weinhold, K., Spindler, G., Schladitz, A., Bastian, S., Löschau, G., Cyrys, J., Gu, J., Flentje, H., Briel, B., Asbach, C., Kaminski, H., Ries, L., Sohmer, R., Gerwig, H., Wirtz, K., Meinhardt, F., Schwerin, A., Bath, O., Ma, N., Wiedensohler, A., 2019. Variability of black carbon mass concentrations, sub-micrometer particle number concentrations and size distributions: results of the German Ultrafine Aerosol Network ranging from city street to High Alpine locations. Atmos. Environ. 202, 256-268. https://doi.org/10.1016/j.atmosenv.2018.12.029
    Sydbom, A., Blomberg, A., Parnia, S., Stenfors, N., Sandström, T., Dahle, S.E., 2001. Health effects of diesel exhaust emissions, Eur. Respir. J. 17, 733-746. https://doi.org/10.1183/09031936.01.17407330
    Thurston, G.D., Ito, K., Lall, R., 2011. A source apportionment of U.S. fine particulate matter air pollution. Atmos. Environ. 45(24), 3924-3936. https://doi.org/10.1016/j.atmosenv.2011.04.070
    Timbrell, J.A., 2009. Principles of Biochemical Toxicology. Fourth edition. Informa Healthcare USA. New York. ISBN: 978-0-8493-7302-2
    Topinka, J., Milcova, A., Schmuczerova, J., Krouzek, J., Hovorka, J., 2013. Ultrafine particles are not major carriers of carcinogenic PAHs and their genotoxicity in size-segregated aerosols. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 754(1-2), 1-6. https://doi.org/10.1016/j.mrgentox.2012.12.016
    Tran, P.T.M., Ngoh, J.R., Balasubramanian, R., 2020. Assessment of the integrated personal exposure to particulate emissions in urban micro-environments: A pilot study. Aerosol Air Qual Res. 20 (2), 341-357. https://10.4209/aaqr.2019.04.0201
    Vallero, D.A., 2011. 18 - Air Pollution: Atmospheric Wastes. In: Letcher, T.M., Vallero, D.A. (Eds.), Waste: A Handbook for Management. Elsevier, Amsterdam, pp. 243-264. https://doi.org/10.1016/B978-0-12-381475-3.10018-X
    Van den Bossche, J., Peters, J., Verwaeren, J., Botteldooren, D., Theunis, J., De Baets, B., 2015. Mobile monitoring for mapping spatial variation in urban air quality: Development and validation of a methodology based on an extensive dataset. Atmos. Environ. 105, 148-161. https://10.1016/j.atmosenv.2015.01.017
    Wahlang, B., Jin, J., Bier, J.I., Hardesty, J.E., Daly, E.F., Schnegelberger, R.D., Falkner, C.K., Prough, R.A., Kirpich, I.A., Cave, M.C. 2019. Mechanisms of environmental contributions to fatty liver disease. Curr. Environ. Health Rep. 6, 80-94. https://doi.org/10.1007/s40572-019-00232-w
    Wardoyo, A.Y.P., Juswono, U.P., Noor, J.A.E., 2018. Varied dose exposures to ultrafine particles in the motorcycle smoke cause kidney cell damages in male mice. Toxicol. Rep. 5, 383-389. https://doi.org/10.1016/j.toxrep.2018.02.014
    Wei, H., Feng, Y., Liang, F., Cheng, W., Wu, X., Zhou, R., Wang, Y., 2017. Role of oxidative stress and DNA hydroxymethylation in the neurotoxicity of fine particulate matter. Toxicology 380, 94-103. https://doi.org/10.1016/j.tox.2017.01.017
    Weichenthal, S., Van Ryswyk, K., Goldstein, A., Shekarrizfard, M., Hatzopoulou, M., 2016. Characterizing the spatial distribution of ambient ultrafine particles in Toronto, Canada: A land use regression model. Environ. Pollut. 208, 241-248. https://10.1016/j.envpol.2015.04.011
    WHO, 2006. WHO Air quality guidelines for particulate matter, ozone, nitrogen dioxide and sulfur dioxide: global update 2005: summary of risk assessment. World Health Organization (WHO). https://apps.who.int/iris/handle/10665/69477 (accessed 30 September 2020)
    Wong, B.S.E., Hu, Q., Baeg, G.H., 2017. Epigenetic modulations in nanoparticle-mediated toxicity. Food Chem. Toxicol. 109, 746-752. https://doi.org/10.1016/j.fct.2017.07.006
    Wu, T., Xu, H., Liang, X., Tang, M., 2019. Caenorhabditis elegans as a complete model organism for biosafety assessments of nanoparticles. Chemosphere 221, 708-726. https://doi.org/10.1016/j.chemosphere.2019.01.021
    Xia, M., Harb, H., Saffari, A., Sioutas, C., Chatila, T. A., 2018. A Jagged 1–Notch 4 molecular switch mediates airway inflammation induced by ultrafine particles. J. Allergy Clin. Immunol. 142(4), 1243-1256.e17. https://doi.org/10.1016/j.jaci.2018.03.009
    Xiao, X., Cao, L., Wang, R., Shen, Z.X., Cao, Y.X., 2016. Airborne fine particulate matter alters the expression of endothelin receptors in rat coronary arteries. Environ. Pollut. 218, 487-496. https://doi.org/10.1016/j.envpol.2016.07.028
    Yadav, I.C., Linthoingambi, N.D., Kumar, V.S., Li, J., Zhang, G. 2018. Concentrations, sources and health risk of nitrated- and oxygenated-polycyclic aromatic hydrocarbon in urban indoor air and dust from four cities of Nepal. Sci. Total Environ. 643, 1013-1023. https://doi.org/10.1016/j.scitotenv.2018.06.265
    Yang, B., Li, X., Chen, D., Xiao, C., 2017a. Effects of fine air particulates on gene expression in non-small-cell lung cancer. Adv. Med. Sci. 62(2), 295-301. https://doi.org/10.1016/j.advms.2016.12.003
    Yang, L., Hou, X.Y.Y., Wei, Y., Thai, P., Chai, F., 2017b. Biomarkers of the health outcomes associated with ambient particulate matter exposure. Sci. Total Environ. 579, 1446-1459. https://doi.org/10.1016/j.scitotenv.2016.11.146
    Zamberland, D. C., Halmenschelager, P.T., Silva, L.F.O., Da Rocha, A Rocha, J.B.T. Copper decreases associative learning and memory in Drosophila melanogaster. Sci. Total Environ. 710, p. 135306, 2020. https://doi.org/10.1016/j.scitotenv.2019.135306
    Zhang, W., Lei, T., Lin, Z.Q., Zhang, H.S., Yang, D.F., Xi, Z.G., Chen, J.H., Wang, W., 2011. Pulmonary toxicity study in rats with PM10 and PM2.5: Differential responses related to scale and composition. Atmos. Environ. 45(4), 1034-1041. https://doi.org/10.1016/j.atmosenv.2010.10.043
    Zhang, L., Guo, C., Jia, X., Xu, H., Pan, M., Xu, D., Shen, X., Zhang, J., Tan, J., Qian, H., Dong, C., Shi, Y., Zhou, X., Wu, C., 2018b. Personal exposure measurements of school- children to fine particulate matter (PM2.5) in winter of 2013, Shanghai, China. PLoS ONE 13(4), e0193586. https://doi.org/10.1371/journal.pone.0193586
    Zhang, Y., Dong, S., Wang, H., Tao, S., Kiyama, R., 2016. Biological impact of environmental polycyclic aromatic hydrocarbons (ePAHs) as endocrine disruptors. Environ. Pollut. 213, 809-824. https://doi.org/10.1016/j.envpol.2016.03.050
    Zhang, H.H., Li, Z., Liu, Y., Xinag, P., Cui, X.Y., Ye, H., Hu, B.L., Lou, L.P., 2018a. Physical and chemical characteristics of PM2.5 and its toxicity to human bronchial cells BEAS-2B in the winter and summer. J. Zhejiang Univ. Sci. B 19 (4), 317-326. https://doi.org/10.1631/jzus.B1700123
    Zhang, Y., Tu, B., Jiang, X., Xu, G., Liu, X., Tang, Q., Bai, L., Meng, P., Zhang, L., Qin, X., Zou, Z., Chen, C., 2019. Exposure to carbon black nanoparticles during pregnancy persistently damages the cerebrovascular function in female mice. Toxicology 422, 44-52. https://doi.org/10.1016/j.tox.2019.04.014
    Zhang, L., Yang, L., Zhou, Q., Zhang, X., Xing, W., Wei, Y., Hu, M., Zhao, L., Toriba, A., Hayakawa, K., Tang, N., 2020. Size distribution of particulate polycyclic aromatic hydrocarbons in fresh combustion smoke and ambient air: A review. J. Environ. Sci. 88, 370-384. https://doi.org/10.1016/j.jes.2019.09.007
    Zhao, Y., Lin, Z., Jia, R., Li, G., Xi, Z., Wang, D., 2014. Transgenerational effects of traffic-related fine particulate matter (PM2.5) on nematode Caenorhabditis elegans. J. Hazardous Mater. 274, 106-114. https://doi.org/10.1016/j.jhazmat.2014.03.064
    Zhao, Y., Wang, F., Zhao, J. 2015. Size-resolved ultrafine particle deposition and Brownian coagulation from gasoline vehicle exhaust in an environmental test chamber. Environ. Technol. 49, 12153-12160. https://doi.org/10.1021/acs.est.5b02455
    Zhou, S., Yuan, Q., Li, W., Lu, Y., Zhang, Y., Wang, W., 2014. Trace metals in atmospheric fine particles in one industrial urban city: Spatial variations, sources, and health implications. J. Environ. Sci. 26(1), 205-213. https://doi.org/10.1016/S1001-0742(13)60399-X
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